Various chemokines (small proteins that guide white blood cells to sites of infection, injury, or inflammation) in this pathway, such as Cxcl1, Cxcl2, Cxcl3, and Cxcl5 and Ccl20 (Meitei et al., 2021; Mohammadi and Kariminik, 2021), showed significant differences in expression levels between the LV149-L and the DSS group. The gene discussed is CXCL2; the disease is infection.