Alterations in gut microbiome composition and barrier function are associated with reproductive and metabolic defects in women with polycystic ovary syndrome (PCOS): a pilot study (Lindheim et al., 2017). (burst strength: 7.62)Serum zonulin is elevated in women with polycystic ovary syndrome and correlates with insulin resistance and severity of anovulation (Zhang et al., 2015) (burst strength: 2.79). The gene discussed is HP; the disease is Insulin resistance.