Additionally, IRF7 gene expression was detected in clusters of patients with SLE, namely, central memory CD8 T cells, classical monocytes, effector memory CD8 T cells, follicular helper T cells, intermediate monocytes, myeloid dendritic cells, naïve B cells, naïve CD8+ T cells, natural killer cells, non-switched memory B cells, non-classical monocytes, plasmacytoid dendritic cells, progenitor cells, switched memory B cells, T regulatory cells, Th1 cells, Th1/Th17 cells, Th2 cells, and Vd2 gd T cells (Fig. 10F). The gene discussed is CD8A; the disease is systemic lupus erythematosus.