Mean age of GLP-1 RA cases was 57.4 years (SD 11.2); 44.6% were male, 67.7% had a recent psychiatric history (including 59.2% with antidepressants use and 21.6% with antipsychotics use) and 51.3% had obesity. The gene discussed is GLP1R; the disease is obesity due to melanocortin 4 receptor deficiency.