Previous studies have demonstrated that NET components such as DNA, MPO, NE, and histones release cytokines that lead to inflammation, epithelial‒mesenchymal transition (EMT), epithelial damage, fibroblast activation, and fibroblast‒myofibroblast transition, all of which promote the progression of lung fibrosis [39]. The gene discussed is MPO; the disease is pulmonary fibrosis.