One study [15] revealed that in asymptomatic patients, higher AIP levels were associated with an increased likelihood of coronary artery calcification (OR: 2.28, 95% CI 1.74–3.00, P < 0.00001).The pooled results of two studies [17, 18] demonstrated that individuals with higher AIP levels were significantly more likely to have multivessel CAD compared to those with lower AIP levels (OR: 2.04, 95% CI 1.50–2.77, I2 = 0%, P < 0.00001). Here, AIP is linked to coronary artery disorder.