AIP and autoimmune pancreatitis: In patients with CCS, higher AIP levels significantly increased the risk of MACE [8, 58, 59] (HR: 1.65, 95% CI 1.15–2.37, I2 = 65%, P = 0.007), but this association was non-significant when AIP was analyzed as a continuous variable [5] (HR per 1-unit increment of AIP: 0.66, 95% CI 0.43–1.02, P = 0.06).