IL10 and colitis: Both the number of bacterial taxa with significant circadian rhythmicity per fecal sample (R = 0.45, p = 0.019) and the fraction that they represented of all detected taxa (R = 0.54, p = 0.005) positively correlated to the remaining lifetime of the corresponding IL-10-/- mouse, before it had to be removed from the experiments (Figure 5a), suggesting that the disruption of gut microbiota rhythmicity is a linear process that is linked to colitis development.