Nine (9/89; 10.1%) of the BRCA1/BRCA2 MINAS cases within this review were reported by Leegte, van der Hout [11] who reported a younger median age of cancer onset in BRCA1/BRCA2 MINAS at 40.8 years vs. 48 years for single BRCA1/BRCA2 carriers. The gene discussed is BRCA1; the disease is cancer.