BRCA1 and breast cancer: We evaluated 29 cases with Lynch-BRCA1/2 variants, of which 34.5% (10/29) presented Lynch-associated malignancies only (colorectal, endometrial, bladder cancers and tubular adenomas), 20.7% (6/29) presented with BRCA1/2-related cancers only such as breast cancers and 44.8% (13/29) presented with malignancies associated with both Lynch and BRCA1/2.