ITGAX and Increased total eosinophil count: Depletion of CD11c+ cell populations during repeat spore exposure resulted in significantly reduced eosinophilia in the BAL fluid and lung tissue, while neutrophilia was increased (Fig. 3C and Supplementary Fig. 5B), in line with previously reported systemic neutrophilia (including in the lung) in DTx treated Cd11c.DOG mice45.