MOG and cholesteryl ester measurement: Valencia-Sanchez et al. reported that initial misdiagnosis occurred in 47% of cases, as isolated CE did not always prompt consideration of central nervous system demyelination and MOG-IgG testing [11].Of the nine patients included in our study, five were initially misdiagnosed because they were not tested for MOG antibodies at the time of the first attack; MOGCE diagnosis was confirmed only at the time of relapse.