First, we selected NB cell lines characterized by high expression levels of CTTNBP2 and MCF2L. Using the public DepMap database (https://depmap.org/portal/), our analysis revealed that most NB cell lines exhibit low expression of CTTNBP2, with the LAN-2 cell line showing the highest expression levels (Supplementary Fig. 1A). This evidence concerns the gene CTTNBP2 and neuroblastoma.