CTTNBP2 and neuroblastoma: To further confirm this hypothesis, gene silencing experiments were performed in NB cell lines, demonstrating that CTTNBP2 (Fig. 6b and Supplementary Fig. 9A) or MCF2L (Fig. 6c and Supplementary Fig. 9B) silencing led to a significant increase in cell proliferation (Fig. 6d) and invasiveness (Fig. 6f).