To make our statistical analysis more robust, we performed a multivariate analysis that studied the prognostic impact of p53 immunoexpression and TP53 mutational status relative to age and two distinct sets of tumor locations, i.e., the genitourinary and gynecological systems vs. the gastrointestinal system, the hepatobiliary system, and the pancreas. The gene discussed is TP53; the disease is neoplasm.