8 Mao Mao S S Huang Huang S S A Meta-analysis of the Association between Angiotensin-converting Enzyme Insertion/ deletion Gene Polymorphism and the Risk of Overweight/obesity A Meta-analysis of the Association between Angiotensin-converting Enzyme Insertion/ deletion Gene Polymorphism and the Risk of Overweight/obesity J Renin Angiotensin Aldosterone Syst J Renin Angiotensin Aldosterone Syst 2015 2015 16 16 3 3 687 687 694 694 10.1177/1470320313501218 10.1177/1470320313501218 24150609 24150609. The gene discussed is ACE; the disease is obesity due to melanocortin 4 receptor deficiency.