This result is consistent with the report of Wang et al., who found that administration of pasteurized A. muciniphila or Amuc_1100 protein could significantly inhibit the occurrence of colon tumors in colitis-associated CRC mice (15), and the proportion of CD8+ T cells in the colon was significantly lower than that in the colitis-associated CRC control group. The gene discussed is CD8A; the disease is colitis.