In a study conducted by Umgelter et al10 in 23 cirrhotic patients with hepatorenal syndrome hospitalized in the intensive care unit, it has been shown that IAP decreased from 22 mm Hg to 9 mm Hg on average and creatinine clearance increased from 23 mL/min to 33 mL/min with therapeutic paracentesis performed after infusion of 20% 200 mL human albumin. The gene discussed is ALB; the disease is hepatorenal syndrome.