The process of mitophagy is regulated by crucial modulators, F‐box containing proteins, including F‐box only protein 7 (FBXO7), sterol regulatory element binding transcription factor 1 (SREBF1), and WD40 domain protein 7 (FBXW7), intricately linked to the PINK1/Parkin pathway's efficiency in PD [90]. This evidence concerns the gene PRKN and Parkinson disease.