Parallel to the findings of miR‐32533 inhibition‐exacerbated cognitive impairment in the APP/PS1 mice, various forms of Aβ, such as monomers, oligomers, and CTFβ, were over‐generated by miR‐32533 sponges (Figure 6N–Q, all p < 0.05 vs. APP/PS1 scrambled control), accompanied by a decrease in ADAM10 and an increase in BACE1 and PS1 (Figure 6N,S–U, all p < 0.05 vs. APP/PS1 scrambled control). This evidence concerns the gene APP and Cognitive impairment.