BTG3 and systemic lupus erythematosus: To help classify SLE cases, the European Alliance of Associations for Rheumatology (EULAR) developed the 2019 EULAR/ACR classification criteria for SLE that includes one entry criteria (a positive ANA titer), seven clinical (constitutional, hematologic, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal) and three immunological (antiphospholipid antibodies, complement proteins, SLE-specific antibodies) domains [4].