Globally, gestational diabetes mellitus (GDM) affects 2% to 9% of pregnant women and is characterized as "any level of glucose intolerance first recognized during pregnancy." The placenta during pregnancy releases certain diabetogenic hormones such as growth hormone, corticotropin-releasing hormone, human placental lactogen, prolactin, and progesterone [1,2]. The gene discussed is CRH; the disease is gestational diabetes.