This mechanism not only significantly reduces levels of total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB) and triglycerides (TG) in the blood (Liu et al., 2019; Oesterle et al., 2017), but also offers long-term benefits in promoting vascular health and preventing atherosclerosis (Cai et al., 2021). This evidence concerns the gene APOB and atherosclerosis.