In addition, as far as the TNF+/VEGFA+ ratio in ccRCC is concerned, both our study and Cheng et al.’s study were close to 1; however, in contrast, more large-sample studies are needed in the future to further clarify the function of MCs in ccRCC, or the discussion needs to be further refined according to the tumor stages. This evidence concerns the gene TNF and nonpapillary renal cell carcinoma.