Serum IgE (903.68 ± 544.34 vs. 2,045.57 ± 974.12, p = 0.0156) and OVA-specific IgE (196.65 ± 119.67 vs. 391.85 ± 152.48, p = 0.0159) production was, however, attenuated in the DKO group than the CRS group (Figure 8C). The gene discussed is IGHE; the disease is congenital rubella syndrome.