A proposed mechanism of the influence of Ruminococcus in unfavourable prostate cancer outcomes is via upregulation of lysophosphatidylcholine acyltransferase 1 (LPCAT1), which may contribute to neoplasia via DNA repair pathways, phosphatidylcholine remodeling, or mRNA synthesis and production of platelet activating factor (37). This evidence concerns the gene LPCAT1 and Familial prostate cancer.