A pre- matching comparison showed that the SILA group was younger (p < 0.01), had lower preoperative inflammatory response (p = 0.04 for WBC, p < 0.01 for CRP), had fewer prior surgeries (p = 0.01), and was less likely to have perforated appendicitis or intraperitoneal abscess formation (p < 0.01). Here, CRP is linked to appendicitis.