Additionally, there were no significant differences in the incidence of pleural effusion (p = 0.470), WBC count (p = 0.306), CRP levels (p = 0.874), NT-proBNP levels (p = 0.927) at 12 h postoperatively, and electrocardiographic abnormalities (p = 0.452). This evidence concerns the gene NPPB and Pleural effusion.