Remarkably, this study indicated that after adjusting for age, race, weight, sex, SOFA score, SAPSII score, cardiovascular disease, chronic pulmonary disease, diabetes, cerebrovascular disease, peripheral vascular disease, norepinephrine use, creatinine, SBP, DBP, ALT, ALP, and AST, the RAR index was positively correlated with increased 180-day mortality in patients with CA. The gene discussed is GPT; the disease is vascular disorder.