The correlation between single nucleotide polymorphisms (SNPs) within selenoprotein genes and cancer susceptibility has been a subject of investigation, encompassing genes like SelP and GPx, as well as TXNRD, selenoprotein N (SEPN1, SelN), selenoprotein S (VIMP, SelS), and selenoprotein W (SEPW1, SelW) (171, 172). This evidence concerns the gene SELP and cancer.