TRIM71 and congenital hydrocephalus: These findings suggest that the Trim71 mutation may play a key role in the pathogenesis of congenital hydrocephalus through specific pathological mechanisms, providing a new direction for the development of precise therapeutic strategies for congenital hydrocephalus (Figure 3) (Liu et al., 2023; Cuevas et al., 2015).Further research is needed to establish definitive evidence of the relationships among ferroptosis, Wnt signaling, and hydrocephalus.