INS and osteoporosis: In addition, after adjusting for possible confounders in the final adjusted model, no significant relationship between dietary insulin indices (DII and DIL) and the odds of osteoporosis was observed (OR = 1.16, 95% CI: 0.93–1.27; P trend = 0.642 for trend and OR = 1.55, 95% CI: 1.09–2.31; P trend = 0.104 for trend, respectively) (Table 3).