For instance, genetic or pharmacological inhibition of astrocytes in the ventral hippocampus (vHPC) compelety attenuated anxiodepressive‐like behaviors in chronic pain mouse model [56].;Beside, GFAP in the central nucleus of amygdala (CeA) were demonstrated to be increased at the chronic (4 weeks post‐SNL), while manipulating anxiety like behavior, but not acute (1 week post‐SNL), stage of NP [57]. Here, GFAP is linked to Anxiety.