This process is necessary for both normal tissue repair and in diseases such as tumor development.[36] Exos have demonstrated the ability to enhance the expression of VEGF in endothelial cells, thereby promoting the process of angiogenesis.[37] In addition, our study noted a rise in NF‐κB expression in HUVECs cultured on the CS‐PEG‐Exo hydrogel. The gene discussed is NFKB1; the disease is neoplasm.