BDNF and Anxiety: In recent years, there have been more studies on the neurotransmitters GABA and Glu related to emotions [53], such as the GABA pathway regulating anxiety like behavior in Parkinson’s rats [53] and the involvement of GABA/Glu in the occurrence of depressive emotions [54]; Related to brain metabolism [55], there is a significant correlation between GABA and low metabolism in the brain; Related to pain [56], such as brain-derived neurotrophic factor (BDNF) converting the normal inhibitory effect of GABA into stimulation, leading to the occurrence of neuropathic pain [57].