Of the men, 8.5% had a history of malignancies, 16 men had suspicious findings at the first clinical assessment, family history of prostate cancer and breast cancer was recorded in 28% and 82% of the patients, respectively, the median PSA level at referral was 0.9 ng/ml (IQR: 0.6‒1.9), and prostate volume 24 ml (IQR: 19‒33; Table 1). Here, KLK3 is linked to Familial prostate cancer.