To explore the mechanism of Ephrin A1 in promoting gastric cancer metastasis, we detected the expression of Ephrin A1 in different gastric cancer cell lines and found that NCI-N87 and AGS cells had low expression levels of Ephrin A1 and MKN45 cells were highly expressed of Ephrin A1 (Fig. EV1A). This evidence concerns the gene EFNA1 and gastric cancer.