Further analysis of the data from TCGA revealed that PCDH17 mRNA expression in CRC tissues was also positively correlated with the N (P < 0.001) and clinical stages (P < 0.001; Fig. 2B, C), suggesting a potential association between PCDH17 expression in endothelial cells and unfavorable prognosis and distant metastasis in CRC. This evidence concerns the gene PCDH17 and colorectal carcinoma.