We investigated the effect of tumor-intrinsic SRSF1 on T cells by co-culturing Hep1-6-OVA cells with OTI CD8+ T cells.28 We conducted RNA sequencing on OTI CD8+ T cells sorted by flow cytometry after 8 h of co-culture (Supplementary Fig. 3h). Here, SRSF1 is linked to neoplasm.