Nine of the 54 Chinese patients were diagnosed with monogenic inflammatory bowel disease, 5/9 had a pathogenic variant in IL10R, 2/9 were diagnosed with chronic granulomatous disease with CYBB variants, one patient had XIAP deficiency, and one had a TNFRSF13B mutation .37 The gene discussed is IL10RA; the disease is hyperinsulinemic hypoglycemia, familial, 4.