CXCL10 and tuberculosis: A meta-analysis to evaluate the diagnostic accuracy of IP-10 for distinguishing active TB from latent TB infection, adjusting various factors, including country economic status, assay condition (M.tb antigen-stimulated/unstimulated), study design, HIV status, and IP-10 cut-off levels showed the significant discriminatory effect of IP-10, suggesting that IP-10 is a good biomarker for TB diagnosis [33].