POU5F1 and neoplasm: Western blot analyses revealed changes in the expression of epithelial‐mesenchymal transition (EMT)‐associated molecules (E‐cadherin, N‐cadherin, and Vimentin) and stemness markers (SOX2, OCT4, and NANOG) resulting from circPCSK6 downregulation, which play crucial roles in driving tumor invasiveness and regulating stem cell dynamics (Figure 2F,G).