EZR and cancer: These included genes involved in cancer progression (PDK4, GPX3, LMAN1, RP11-124N14.3 and PAK6), factors implicated in cytokine response (TNFRSF12A, UBE2J1 and MAP1B), as well as those important for cytoskeleton remodelling, decreased intercellular adhesion and cancer stem cell transformation (EZR and CD44).