Disruptions in this process can result in tumorigenesis or aneuploidy.[28] Given that cohesion is also essential for chromosome recombination repair, impaired ESCO1 function leads to a significant increase in improper chromosome repair.[29] Some evidence suggests that ESCO1 is involved in tumorigenesis.[30] However, its role in cervical cancer remains unknown. The gene discussed is ESCO1; the disease is cervical carcinoma.