This understanding contributes to a better comprehension of the pathogenesis of systemic diseases and tumors.[24] As a member of the IRG family, immunity‐related GTPase Q (IRGQ) possesses a conserved G‐IRG domain and was initially found to be highly expressed in hepatocellular carcinoma tissues.[25] However, the role of IRGQ in cervical cancer and ferroptosis is still unclear. The gene discussed is IRGQ; the disease is hepatocellular carcinoma.