TRPC6 and pulmonary arterial hypertension: Maximum TRALI feature reduction requires treatment with NF449 before LPS sensitization and anti‐MHC I mAb administration.[148, 180] TRPC6, another calcium channel expressed by smooth muscle cells, positively controls vasoconstriction, pulmonary arterial hypertension, and edema formation.[181] The TRPC6 inhibitor SAR7334 reduces protein accumulation in BALs and periarteriolar edema in TRALI.[181a]