CD4+CD25+Foxp3+ Tregs reportedly aggregate in the bronchoalveolar lavage fluid (BALF) of mice and patients with ALI, alleviating lung injury by mitigating inflammation.[97] CD4+CD25+Foxp3+ Tregs resist antibody‐dependent mouse TRALI by producing IL10.[56c] Expanding Tregs in vivo with IL2/IL2c increases IL10 and decreases IL17A levels, preventing antibody‐mediated TRALI.[57] Moreover, subtypes such as Tr1 and iTR+35 cells display TRALI preventive potential, with rIL‐35 inhibiting EC activation in a mouse model.[89]. The gene discussed is CD4; the disease is acute respiratory distress syndrome.