Previous studies have shown that TTK could regulate the progression of esophageal squamous cell carcinoma and melanoma through its kinase activity.[18, 19] To delve deeper into the kinase regulatory mechanism of TTK in TCL, we conducted the quantification of the phosphoproteome in Jurkat cell and identified 1129 differentially phosphorylated proteins after TTK knockdown (Figure S5A,B, Supporting Information). Here, TTK is linked to melanoma.