NBEAL2 and infection: In the case of RRV, studies of the roles of RRV gps during infection are thus far more limited but have demonstrated that RRV gH/gL is critical for regulating infection of certain cell types, such as B cells and endothelial cells, through interactions with Ephs expressed on these cells, while infection of other cell types, such as fibroblasts and epithelial cells, is not completely dependent on this interaction (33, 37).