Therefore, to assess the ability of RRV gL mutant and RRV chimeras expressing KSHV gH and gL gps to infect B cells, we utilized human BJAB cells, a cell line that has been used as a model for B cell infection studies of both RRV and KSHV (47, 48) and in which RRV is capable of establishing a latent infection. The gene discussed is NBEAL2; the disease is disease arising from reactivation of latent virus.