Based on the relative activation or suppression of MVD and TcellinfGEP in the models, the mouse tumor models were categorized into three subgroups: MVD-high/TcellinfGEP-low (BNL 1ME A.7R.1, Renca, and B16-F10), MVD-low/TcellinfGEP-high (Hepa 1-6, MC38, CT26.WT, RAG, and MBT2), and MVD-low/TcellinfGEP-low (KLN205, LL/2, EMT6, and 4T1; Fig. 4A). The gene discussed is DDX53; the disease is neoplasm.