We detected significantly higher S1P levels in the NSCLC group than in the control group (3770.99 ± 762.29 ng/mL vs. 366.53 ± 249.38 ng/mL, patients with NSCLC vs controls, respectively, p < 0.001) (Figure 1). Here, MBTPS1 is linked to non-small cell lung carcinoma.