Anti-Mi-2, anti-TIF1γ, anti-NXP2, anti-MDA5, and anti-SAE are characteristic MSA for DM with anti-TIF1γ, anti-NXP2, and anti-SAE1 related to malignancies (8, 10), and anti-MDA5 associated with severe interstitial lung disease (ILD) (8). The gene discussed is IFIH1; the disease is cancer.