CircGARS (hsa_circ_0009000) was significantly upregulated in SLE PBMCs, which directly combined with miR-19a to regulate the expression of YTH domain-containing family protein 2 (YTHDF2) and promoted the development of SLE via the A20/NF-κB axis (122). The gene discussed is NFKB1; the disease is systemic lupus erythematosus.