We have previously shown that not only IL-6 is important in this regard, but rather that e.g. high levels of IL-6, sIL-6R and sgp130 are independent predictors of COVID-19 severity in survivor patients, whereas e.g. high levels of IL-6 and low levels of sIL-6R and sgp130 were predictors of death in a subgroup of patients with a very poor prognosis (42). The gene discussed is IL6ST; the disease is COVID-19.