The general characteristics of patients in both cohorts were analyzed, and no statistically significant differences were observed in terms of age, hepatic encephalopathy, bacterial infections, gastrointestinal bleeding, hepatorenal syndrome, ALT, AST, ALB, GGT, ALP, INR, PTA, WBC, NLR, CR, Na, MELD score, MELD-Na score, and ALBI score (p > 0.05) (Table 1). The gene discussed is GPT; the disease is Renal insufficiency.